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rabbit anti brain derived neurotrophic factor bdnf  (Alomone Labs)


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    Alomone Labs rabbit anti brain derived neurotrophic factor bdnf
    Mature <t>BDNF</t> and proBDNF levels were measured by Western blot in brain lysates derived from mice exposed to either vehicle or DFP (4.0 mg/kg), followed by treatment with saline, GM1, or GD3 (5 mg/kg/day for 7 days). (A) Representative blot illustrating proBDNF (32 kDa) and BDNF (14 kDa). CTX, cortex; PFC, prefrontal cortex; HIP, hippocampus; SVZ, subventricular zone. (B) The data presented in the bar graphs were obtained from densitometry measurements of the bands for proBDNF, BDNF, and actin . Ratios of proBDNF and BDNF to actin were calculated for each replicate sample. Results are expressed as means ± S.E.M. of ≥3 replicates per condition. *P < 0.05 and **P < 0.01 indicates significant differences between indicated groups, as calculated using one-way ANOVA with Tukey’s multiple comparison test.
    Rabbit Anti Brain Derived Neurotrophic Factor Bdnf, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 95/100, based on 165 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/rabbit anti brain derived neurotrophic factor bdnf/product/Alomone Labs
    Average 95 stars, based on 165 article reviews
    rabbit anti brain derived neurotrophic factor bdnf - by Bioz Stars, 2026-03
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    Images

    1) Product Images from "GM1 and GD3 Gangliosides Attenuate NGF-TrkA and BDNF-TrkB Signaling Dysfunction Associated with Acute Diisopropylfluorophosphate Exposure in Mouse Brain"

    Article Title: GM1 and GD3 Gangliosides Attenuate NGF-TrkA and BDNF-TrkB Signaling Dysfunction Associated with Acute Diisopropylfluorophosphate Exposure in Mouse Brain

    Journal: bioRxiv

    doi: 10.1101/2025.03.31.646417

    Mature BDNF and proBDNF levels were measured by Western blot in brain lysates derived from mice exposed to either vehicle or DFP (4.0 mg/kg), followed by treatment with saline, GM1, or GD3 (5 mg/kg/day for 7 days). (A) Representative blot illustrating proBDNF (32 kDa) and BDNF (14 kDa). CTX, cortex; PFC, prefrontal cortex; HIP, hippocampus; SVZ, subventricular zone. (B) The data presented in the bar graphs were obtained from densitometry measurements of the bands for proBDNF, BDNF, and actin . Ratios of proBDNF and BDNF to actin were calculated for each replicate sample. Results are expressed as means ± S.E.M. of ≥3 replicates per condition. *P < 0.05 and **P < 0.01 indicates significant differences between indicated groups, as calculated using one-way ANOVA with Tukey’s multiple comparison test.
    Figure Legend Snippet: Mature BDNF and proBDNF levels were measured by Western blot in brain lysates derived from mice exposed to either vehicle or DFP (4.0 mg/kg), followed by treatment with saline, GM1, or GD3 (5 mg/kg/day for 7 days). (A) Representative blot illustrating proBDNF (32 kDa) and BDNF (14 kDa). CTX, cortex; PFC, prefrontal cortex; HIP, hippocampus; SVZ, subventricular zone. (B) The data presented in the bar graphs were obtained from densitometry measurements of the bands for proBDNF, BDNF, and actin . Ratios of proBDNF and BDNF to actin were calculated for each replicate sample. Results are expressed as means ± S.E.M. of ≥3 replicates per condition. *P < 0.05 and **P < 0.01 indicates significant differences between indicated groups, as calculated using one-way ANOVA with Tukey’s multiple comparison test.

    Techniques Used: Western Blot, Derivative Assay, Saline, Comparison



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    Image Search Results


    Mature BDNF and proBDNF levels were measured by Western blot in brain lysates derived from mice exposed to either vehicle or DFP (4.0 mg/kg), followed by treatment with saline, GM1, or GD3 (5 mg/kg/day for 7 days). (A) Representative blot illustrating proBDNF (32 kDa) and BDNF (14 kDa). CTX, cortex; PFC, prefrontal cortex; HIP, hippocampus; SVZ, subventricular zone. (B) The data presented in the bar graphs were obtained from densitometry measurements of the bands for proBDNF, BDNF, and actin . Ratios of proBDNF and BDNF to actin were calculated for each replicate sample. Results are expressed as means ± S.E.M. of ≥3 replicates per condition. *P < 0.05 and **P < 0.01 indicates significant differences between indicated groups, as calculated using one-way ANOVA with Tukey’s multiple comparison test.

    Journal: bioRxiv

    Article Title: GM1 and GD3 Gangliosides Attenuate NGF-TrkA and BDNF-TrkB Signaling Dysfunction Associated with Acute Diisopropylfluorophosphate Exposure in Mouse Brain

    doi: 10.1101/2025.03.31.646417

    Figure Lengend Snippet: Mature BDNF and proBDNF levels were measured by Western blot in brain lysates derived from mice exposed to either vehicle or DFP (4.0 mg/kg), followed by treatment with saline, GM1, or GD3 (5 mg/kg/day for 7 days). (A) Representative blot illustrating proBDNF (32 kDa) and BDNF (14 kDa). CTX, cortex; PFC, prefrontal cortex; HIP, hippocampus; SVZ, subventricular zone. (B) The data presented in the bar graphs were obtained from densitometry measurements of the bands for proBDNF, BDNF, and actin . Ratios of proBDNF and BDNF to actin were calculated for each replicate sample. Results are expressed as means ± S.E.M. of ≥3 replicates per condition. *P < 0.05 and **P < 0.01 indicates significant differences between indicated groups, as calculated using one-way ANOVA with Tukey’s multiple comparison test.

    Article Snippet: For this study, the following antibodies were purchased: rabbit anti-TrkA (RRID:AB_310180; Millipore Millipore, St. Louis, MO, USA, #06-574), mouse anti-NeuN (RRID:AB_2298772; Sigma-Aldrich, St. Louis, MO, USA, #MAB377), rabbit anti-p75 neurotrophin receptor (p75 NTR , RRID:AB_310649; Millipore #07-476), rabbit anti-sortilin (RRID:AB_2192606; Abcam, Cambridge, MA, USA, #ab16640), goat anti-TrkB (RRID:AB_2155263; R&D Systems, Minneapolis, MN, USA, #BAF1494), rabbit anti-actin (RRID:AB_476693; Sigma #A2066), rabbit anti-NGF (RRID:AB_2040019, Alomone Labs, Jerusalem, Israel, #AN-240), rabbit anti-brain-derived neurotrophic factor (BDNF) (RRID:AB_2039756, Alomone Labs #ANT-010), and rabbit anti-phospho-Trk (RRID:AB_2298805; Cell Signaling Technology, Danvers, MA, USA, #9141).

    Techniques: Western Blot, Derivative Assay, Saline, Comparison